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Senna alata |
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Hennebelle, T., B. Weniger, H. Joseph, S. Sahpaz and F. Bailleul. 2009. Senna alata.Fitoterapia, 80: 385–393. Abstract ; A review is made of chemical, ethnopharmacological and pharmacological papers dealing with Senna alata (L.) Roxb.,a plant that belongs to the Creole traditional system of medicine and that has recently been introduced in the French Pharmacopoeia. The proofs existing for its various usages are presented. The species is mainly used against constipation and skin diseases. The laxative activity is supported by scientific findings. In contrast the dermatologic use requires further investigation. The species can be considered as safe for short-term or topical use. .................................................................................................................................... ELUJOBA, A. A., O. O. AJULO and G. O. IWEIBO. 1989. Chemical and biological analyses of Nigerian Cassia species for laxative activity. Journal of Pharmaceutical Biomedical Analysis 7, 12: 1453-1457. Abstract: The leaves of 10 Cassia species (Leguminosae), cultivated in Nigeria, were assayed spectrophotometrically for combined anthraquinone content and also pharmacologically for their laxative properties in male albino rats using official senna leaves (Cassia acutifoliu Del.) as the reference standard. Leaves of C. podocarpa Guill. and Perr. and of senna had identical laxative potency. The results of both the chemical and the biological experiments suggested that C. alata L. and C. podocurpa are the most likely candidates for drug development in Nigeria. The use of a laxative index is proposed for the comparative study of Cassia (or any plant species) and its possible application to the quality control of these drugs is discussed.
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